Programme Schedule
TUESDAY, March 20
8:00am // Registration
8:30am // Welcome Message by Prof. Shazib Pervaiz
8.45am // Opening Address by Prof. Shing Chuan Hooi
Chair, Medical Science Cluster, YLLSoM, NUS
Session 1: Inflammation and Immune Evasion
Chair: Shazib Pervaiz
9:00am // Christopher Kevil [KEYNOTE SPEAKER]
Hydrogen sulfide regulation of vascular inflammatory responses: role in ischemic and shear stress adaptation
9:50am // Haiyan Liu
Inflammatory cytokines as targets for cancer immunotherapy
10:20am // Lina Lim
Annexin-A1 in the tumor microenvironment of breast cancer: regulation of inflammation and metastasis
10:50am // Coffee Break
Chair: Gautam Sethi
11:15am // Paul MacAry
"Magic Bullets in Oncology"
11:45am // Siew Cheng Wong
Modulating Warburg metabolism in macrophages to control pancreatic ductal adenocarcinoma
12:15pm // Anis Larbi
"Immunosenescence: does it exist?"
12:45pm // Maybelline Giam [Sponsors Talk]
The Attune NxT Flow Cytometer: freakishly fast flow rates for immuno-oncology research
1:00pm // Lunch Break
Session 2: Mediators of Cellular Senescence and Oncogenesis
Chair: Kah Leong Lim
2:00pm // Marie-Véronique Clément
Reactive Oxygen Species and the regulation of cellular senescence: what's new?
2:30pm // Han Ming Shen
Post-translation regulation of autophagy machinery: from molecular mechanisms to potential applications
3:00pm // Ayako Ishizu
Thrombopoietin induces oxidative metabolism in hematopoietic stem cell differentiation
3:15pm // Yvonne Tay
A microRNA:gene:pseudogene network regulates tumorigenesis in prostate cancer
3:30pm // Polly Chen Lei Lei
Understanding the mechanisms for fine-tuning A-to-I RNA editing in cancer
3:45pm // Coffee Break
Chair: Theresa Tan
4:15pm // Jia Jia Liu
Dynamic changes and function of PI4P during synaptic potentiation
4:45pm // Caroline Lee
Towards personalized medicine: employing big-data genomics to predict population differences in drug response
5:15pm // Yun Chau Long
Metabolism connects glutamine to mTORC1 signalling
5:30pm // Stephen Chong
Bcl-2 phosphorylation regulates mitochondrial OXPHOS
5:45pm // End of Day 1
Wednesday, March 21
Session 3: Stemness and Metastasis
Chair: Bay Boon Huat
9:00am // Kanaga Sabapathy
Therapeutic targeting of p53
9:30am // Chin Tong Ong
Regulation of Tet3 activity by phosphorylation
10:00am // Marius Sudol
YAP proto-oncogene protein as a mediator of cell and organ rigidity and metastasis
10:30am // Derrick Ong
H2AFV expression defines functionally distinct cancer subpopulations
10:45am // Coffee Break
Chair: Celestial Yap
11:15am // Wee Joo Chng
Pathological role of RNA editing in multiple myeloma
11:45am // Heng-Phon Too
Circulatory miRNA biomarkers as "liquid biopsy"
12:15pm // Sudhakar Jha
TIP60 represses telomerase expression: a HAT with new tricks
12:30pm // Deepika Raman
Redox-mediated stability of c-Myc and its activity
12:45pm // Lihan Zhou [Sponsors Talk]
Small but powerful, circulating miRNA assay for early cancer detection
1:00pm // Lunch Break
Session 4: Redox Metabolism and OXPHOS
Chair: Marie-Véronique Clément
2:00pm // Frédéric Batteux [KEYNOTE SPEAKER]
The role of reactive oxygen species in systemic inflammatory and fibrotic diseases: The scleroderma example
2:50pm // Shazib Pervaiz
Functional dichotomy of cancer cells' redox metabolism
3:20pm // Anand Jeyasekaran
Proliferative stress is associated with a dependency on DNA repair by homologous recombination
3:35pm // Thilo Hagen
Mechanisms underlying the Warburg effect in cancer cells
3:50pm // Coffee Break
Chair: Thomas Loh
4:15pm // Ines Batinic-Haberle
Development of Mn porphyrins into clinical trials as normal tissue injury and anticancer therapeutics
5:00pm // Boon Cher Goh
Oxidative phosphorylation as an emerging target for tumor resistance
5:30pm // Dennis Kappei
From protein evolution to novel telomere length regulators
5:45pm // Andrea Wong
The role of oxidative phosphorylation inhibitors as anti-cancer therapy in solid tumors
6:00pm // Closing Remarks by Shazib Pervaiz